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. 2018 Oct 23;2018(10):CD008570. doi: 10.1002/14651858.CD008570.pub3

Summary of findings 2. Arm support with conventional mouse versus conventional mouse alone.

Patient or population: office workers
 Settings: VDU users (more than 20 hours per week)
 Intervention: arm support board (with conventional computer mouse)
 Comparison: no arm support board (with conventional mouse)
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) No of Participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
No arm support board (with conventional mouse) Arm support board (with conventional mouse)
Incidence of upper body disorders
 Questionnaire followed by medical examination
 Follow‐up: 12 months 333 per 1000 290 per 1000
 (140 to 600) RR 0.87 
 (0.42 to 1.80) 191
 (2 studies) ⊕⊕⊝⊝
 low1,2  
Incidence of neck or shoulder disorder
 Questionnaire followed by medical examination
 Follow‐up: 12 months 232 per 1000 211 per 1000
 (28 to 1000) RR 0.91 
 (0.12 to 6.98) 186
 (2 studies) ⊕⊕⊝⊝
 low1,2  
Incidence of right upper extremity disorders
 Questionnaire followed by medical examination
 Follow‐up: 12 months 185 per 1000 195 per 1000
 (116 to 308) OR 1.07 
 (0.58 to 1.96) 178
 (2 studies) ⊕⊕⊕⊝
 moderate2  
Neck or shoulder discomfort score
 Questionnaire
 Follow‐up: 12 months   The mean neck or shoulder discomfort score in the intervention groups was
 0.02 standard deviations higher
 (0.26 lower to 0.3 higher) 5   195
 (2 studies) ⊕⊕⊝⊝
 low2,3 SMD 0.02 (−0.26 to 0.30) ‐ no significant difference
Right upper extremity discomfort score
 Questionnaire
 Follow‐up: median 12 months   The mean right upper extremity discomfort score in the intervention groups was
 0.07 standard deviations lower
 (0.35 lower to 0.22 higher) 5   195
 (2 studies) ⊕⊕⊝⊝
 low2,3 SMD −0.07 (−0.35 to 0.22) ‐ no significant difference
Right upper‐limb strain scale
Questionnaire
Follow‐up: 6 weeks
  The mean right upper‐limb strain scale in the intervention groups was
3.00 lower
(34.47 lower to 28.47 higher) 5
  14
(1 study)
⊕⊝⊝⊝
 very low2,3,4  
Work related function no data no data        
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; RR: Risk ratio; OR: Odds ratio; SMD: standardised mean difference; MD: mean difference
GRADE Working Group grades of evidence
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

1 Downgraded one level because of high I² value (more than 50%), indicating heterogeneity.
 2 Downgraded one level because of total number of participants less than 300 (small sample size for a categorical variable).
 3 Downgraded one level because of limitations in studies (measure of outcome based on subjective symptoms (detection bias)).
 4 Downgraded one level because of there is no information on sequence generation (selection bias).
 5 Lower score indicates beneficial effects.