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. 2016 May 20;2016(5):CD009491. doi: 10.1002/14651858.CD009491.pub2

3. Oral midazolam versus chloral hydrate doses.

Study Oral midazolam Oral chloral hydrate
Akil 2005 0.6 mg/kg (max 15 mg) 25 mg/kg (max 0.5 g)
D'Agostino 2000 0.5 mg/kg (max 10 mg) 75 mg/kg (max 2 g)
Derakhshanfar 2013 0.5 mg/kg midazolam. Additional dose up to 8 mg for inadequate sedation 80 mg/kg chloral hydrate followed by further dose 20 mg/kg if required 20 minutes later
Wheeler 2001 0.5 mg/kg midazolam; second dose 30 minutes after the initial dose, either 0.25 mg/kg 75 mg/kg oral chloral hydrate; 30 minutes after the initial dose 25 mg/kg