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. 2016 May 20;2016(5):CD009491. doi: 10.1002/14651858.CD009491.pub2

Aktogu 1994.

Methods Parallel‐group single‐centre randomized controlled trial conducted in Turkey
Participants 32 adults undergoing bronchoscopy (mean age midazolam group 49.4 ± 13.3 and diazepam group 50.9 ± 12.1; 50% men in both groups)
Interventions Midazolam 0.06 mg/kg administered intravenously
Diazepam 0.15 mg/kg administered intravenously
Outcomes Measured 5 and 10 minutes after start of procedure:
Level of sedation on a sedation assessment scale (only the percentage of participants who scored in the 'awake' rank of a sedation scale that ranged from 0 to 4 (0 = awake and 4 = reactive to pain but no verbal communication) that was measured 5 minutes after sedation was administered)
Measured 24 hours after procedure:
Anterograde amnesia (defined by number of participants who recalled the procedure)
Notes Conflicts of interest or funding sources were not reported.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Unclear (no mention of randomization method, just a statement that participants were randomized)
Allocation concealment (selection bias) Unclear risk Unclear (no mention of allocation method, just a statement that participants were randomized)
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Unclear (no mention)
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Only statistical analysis of the questionnaires was reported to have been performed by a blinded statistician
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No withdrawals
Selective reporting (reporting bias) Unclear risk No clear evidence that measured outcomes were not reported (trial protocols were not sought for confirmation)
Other bias Low risk None expected