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. 2016 May 20;2016(5):CD009491. doi: 10.1002/14651858.CD009491.pub2

Gilvarry 1990.

Methods Single‐centre parallel‐group randomized controlled trial conducted in the United Kingdom
Participants 60 adults undergoing upper gastrointestinal endoscopy (mean age: 41.4 in diazepam group and 42.2 in midazolam group; 46% men in diazepam group and 43% men in diazepam group)
Interventions 10 mg intravenous midazolam
20 mg intravenous diazepam
Outcomes Measured 24 hours after the procedure:
Participant satisfaction (measured in the trial as the participant considered sedation was inadequate)
Anterograde amnesia (recalled procedures)
Notes Conflicts of interest or funding sources were not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "Stratified randomised order"
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk An author who did not know which medication had been administered assessed outcomes 24 hours after the procedure
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No withdrawals
Selective reporting (reporting bias) Unclear risk No clear evidence that measured outcomes were not reported (trial protocols were not sought for confirmation)
Other bias Low risk None expected