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. 2018 Oct 26;2018(10):CD007554. doi: 10.1002/14651858.CD007554.pub3

Kim 2003.

Methods
  • Study design: parallel RCT

  • Study duration: not reported

  • Follow‐up period: 12 months

Participants
  • Country: South Korea

  • Setting: multicentre (2 hospitals)

  • Incident adult patients on CAPD

  • Number: treatment group (16); control group (10)

  • Mean age ± SD (years): treatment group (51.6 ± 3.6); control group (56.1 ± 5.2)

  • Sex (M/F): not reported

  • Exclusion criteria: not reported

Interventions Treatment group
  • Low GDP PD solution (pH 7.0, two compartment bag, StaySafe Balance solution; Fresenius Medical Care)


Control group
  • Standard glucose‐containing dialysis fluid (pH 5.5, single compartment bag, stay‐safe; Fresenius Medical Care)

Outcomes
  • RRF

  • Peritoneal transport (4‐hour dialysate:plasma creatinine)

Notes
  • Funding received from Fresenius Medical Care Korea and Medical Research Institute grant, Kyungpook National University Hospital (1998)

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to permit judgement, stratified for diabetes mellitus
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Open‐label, however unlikely to have influenced the objective outcome measured
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Insufficient information to permit judgement
Incomplete outcome data (attrition bias) 
 All outcomes High risk Dropout rates ‐ 38/64 (59%). Missing participants not accounted for. Per protocol analysis
Selective reporting (reporting bias) High risk No report of peritonitis or survival
Other bias Unclear risk Insufficient information to permit judgement