Szeto 2015.

Methods	Study design: parallel RCT Study duration: February 2011 to July 2013 Follow‐up period: 12 months
Participants	Country: Hong Kong Setting: single centre Incident CAPD patients Number: treatment group (31); control group (33) Mean age ± SD (years): treatment group (62.9 ± 12.1); control group (57.7 ± 9.9) Sex (M/F): treatment group (17/14); control group (13/20) Exclusion criteria: patients who were unlikely to survive; planned to have elective living‐related kidney transplant; planned to transfer to other renal centre within 6 months
Interventions	Treatment group Neutral pH, low GDP PD solution (Balance solution) Control group Conventional PD solution (StaySafe)
Outcomes	Fluid status Body composition Nutritional status and arterial stiffness Urine output RRF Peritoneal small solute clearance Peritoneal UF 4‐hour dialysate:plasma creatinine Peritonitis rate Hospitalisation
Notes	"This study was supported in part by the Fresenius Medical Care, and CUHK research account 6901031. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript"
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Using a standard randomisation table
Allocation concealment (selection bias)	Low risk	Randomised by third party using randomisation table
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Open‐label, unlikely to affect outcome
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Incomplete outcome data (attrition bias) All outcomes	Low risk	9% dropout rate
Selective reporting (reporting bias)	Low risk	All relevant outcomes reported
Other bias	High risk	Different in baseline characteristic between two groups