| Study | Reason for exclusion |
|---|---|
| BIOKID 2004 | Wrong intervention: comparing two types of biocompatible PD solutions |
| Braide 2009 | Wrong intervention: citrate supplementation rather than use of biocompatible PD fluids |
| Chang 2016 | Wrong intervention: icodextrin versus non‐icodextrin in the background of using low GDP biocompatible solutions |
| Chow 2014 | Wrong intervention: icodextrin as part of treatment of peritonitis |
| Coester 2006 | Wrong intervention: effect of glucose sparing therapy (NEP) |
| Dallas 2004 | Wrong intervention: icodextrin versus Icodextrin/glucose combination novel fluid |
| de Fijter 1993 | Study conducted over a short period with a view to assessing macrophage function hence study duration too short to evaluate pre‐specified outcomes |
| EDEN 2013 | Wrong intervention: glucose sparing therapy (NEP) |
| Fang 2008 | Wrong intervention: neutral pH, low GDP PD solution as peritoneal equilibration test solution |
| Feriani 1993 | Wrong intervention: two solutions with differences in buffers (bicarbonate against lactate) |
| Fischbach 2004 | Study conducted over two days to examine the effect of PD solutions on intraperitoneal pressure. Duration of study was too short to evaluate pre‐specified patient level clinical outcomes |
| Hiss 2013 | Wrong intervention: normal versus reduced glucose content in the dialysis solution |
| Hwang 2006 | Wrong intervention: icodextrin as peritoneal equilibration test solution |
| IMPENDIA 2013 | Wrong intervention: glucose sparing therapy (NEP) |
| Jenkins 2003 | Wrong intervention: icodextrin versus novel combination solution composed of icodextrin and dextrose |
| John 2008 | Study conducted over one day to examine the effect of biocompatible PD solutions on baroreflex sensitivity. Duration of study was too short to evaluate pre‐specified patient level clinical outcomes |
| le Poole 2004 | Wrong intervention: amino acid‐based dialysis solution |
| Liberek 2002 | Study conducted following 2 overnight dwells (one week apart) of biocompatible and conventional PD solutions to measure inflammatory markers in the PD effluent. Duration of study was too short to evaluate pre‐specified patient level clinical outcomes |
| Lui 2012 | Wrong intervention: amino acid‐containing dialysis solution |
| Martikainen 2005 | Wrong intervention: amino acid‐containing dialysis solution |
| Parikova 2007 | Wrong intervention: neutral pH, low GDP PD solution as a peritoneal equilibration test solution |
| Pedersen 1985 | Wrong intervention: comparing buffers in PD solution |
| Peers 1997 | Wrong intervention: novel icodextrin/glucose combination fluid |
| Plum 1997 | Wrong intervention: amino acid‐containing dialysis solution |
| Rodriguez‐Carmona 2007 | Wrong intervention: amino acid‐based dialysis solution |
| Sav 2009 | Wrong intervention: twice‐daily icodextrin versus daily icodextrin |
| Sav 2010 | Wrong intervention: twice‐daily icodextrin versus daily icodextrin |
| Selby 2005 | Study conducted over two days to examine the effect of PD solutions on haemodynamic parameters. Duration of study was too short to evaluate pre‐specified patient level clinical outcomes |
| Selby 2007a | Wrong intervention: amino acid fluid |
| Smit 2000 | Wrong intervention: glycerol‐based fluid |
| Smit 2001 | Wrong intervention: different strengths of glucose solutions |
| Ueda 2000 | Wrong intervention: amino acid fluid study |
| Van Biesen 2004 | Wrong intervention: amino acid fluid study |
| Yehia 2014 | Wrong intervention: icodextrin versus exchange‐free dialysis regimen in the setting of peritonitis |
| Yoon 2014 | Wrong intervention: icodextrin versus non ‐icodextrin in the background of using biocompatible solution (physioneal) |
GDP ‐ glucose degradation products; NEP ‐ neutral endopeptidase; PD ‐ peritoneal dialysis