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. 2018 Nov 9;2018(11):CD010578. doi: 10.1002/14651858.CD010578.pub2

11. Lazzerini 2013: details of interventions (as reported in systematic review).

Review ID Lazzerini 2013
Types of interventions considered Any type of food used for children with moderate acute malnutrition, including:
  1. improved adequacy of local diet (local foods prepared at home according to a given recipe; home processing of local foods such as soaking, germination, malting and fermentation)

  2. LNS (foods with high lipid content, characterised by a high energy density; also called RUTFs)

  3. blended food supplements (CSB or other blended foods such as wheat‐soy flour, sugar, oil, legumes, or others. These foods are usually solid or semi‐solid foods with low water content, which can be cooked every day at home in the form of porridge or soups for children)

  4. complementary food supplements (food‐based complements to the diet that can be mixed with, or consumed in addition to, the diet. This category can include any of the foods listed above when provided in low doses (i.e. providing only part of the total daily caloric needs))

Details regarding the interventions
  1. LNS (Supplementary Plumpy), blended foods (CSB++, Misola, home foods)

    1. Intervention 1: LNS = Supplementary Plumpy, full dose (energy = 500 kcal, MN = yes, duration = 12 weeks)

    2. Intervention 2: blended foods = CSB++ or Misola (locally produced flour mixture of 60% millet, 20% soy, 10% peanut kernel, 9% sugar and 1% salt), or home foods (millet and cowpea flour + sugar + oil + MN powder) (energy = 500 kcal/day, MN = yes, duration 12 weeks)

    3. Concomitant interventions: nutrition education, health education, medical care

    4. Comparison: LNS full dose vs blended foods

  2. LNS (Supplementary Plumpy), blended foods (CSB premix)

    1. Intervention 1: LNS = Supplementary Plumpy (energy = 1000 kcal, MN = yes, duration = upon recovery)

    2. Intervention 2: blended foods = CSB premix consisting of CSB plus sugar and oil (energy = 1227 kcal/day, MN = yes, duration = variable)

    3. Concomitant interventions: extra MN, nutrition education, health education, medical care

    4. Comparison: LNS full dose vs blended foods

  3. Complementary foods (Pusti Packet), standard care

    1. Intervention 1: complementary blended foods = Pusti Packet comprising toasted rice powder = 20 g, toasted lentil powder = 10 g, molasses = 5 g, and soy bean oil = 3 g (total energy/packet = 150–300 kcal, MN = yes, duration = 12 weeks)

    2. Intervention 2: standard care (nutrition education, health education, medical care or MNs)

    3. Intervention 3: complementary blended foods + standard care + psychosocial stimulation: play session, parenteral counselling, group sessions

    4. Control: multiple MN

    5. Comparison: complementary blended vs standard care

  4. LNS (Supplementary Plumpy), blended foods (CSB premix)

    1. Intervention 1: LNS = Supplementary Plumpy, complementary dose (energy = 500 kcal, MN = yes, duration = 16 weeks)

    2. Intervention 2: blended foods = CSB premix consisting of CSB plus sugar and oil (energy = 1413 kcal/day, MN = yes, duration = 16 weeks)

    3. Concomitant interventions: basic nutrition education, basic health education, basic medical care

    4. Comparison: LNS complementary dose vs blended foods

  5. LNS (soy LNS, soy/whey LNS (Plumpy'Sup)), blended foods (CSB++)

    1. Intervention 1:LNS = soy LNS or soy/whey LNS (Plumpy'Sup) (energy = 75 kcal/kg, MN = yes, duration = 12 weeks)

    2. Intervention 2: blended food = CSB++ (energy = 75 kcal/kg, MN = yes, duration = 12 weeks)

    3. Concomitant interventions: nutrition education

    4. Comparison: LNS full dose vs blended foods

  6. LNS (milk/peanut LNS, soy/peanut LNS), blended foods (CSB)

    1. Intervention 1: LNS = milk/peanut LNS or soy/peanut LNS (energy = 75 kcal/kg, MN = yes, duration = 8 weeks)

    2. Intervention 2: blended food = CSB (energy = 75 kcal/kg, MN = yes, duration = 8 weeks)

    3. Concomitant interventions: NR or no

    4. Comparison: LNS full dose vs blended foods

  7. LNS (Plumpy'Nut), blended foods (CSB premix)

    1. Intervention 1: LNS = Plumpy'Nut (energy = 1000 kcal, MN = no, duration = upon recovery)

    2. Intervention 2: blended food = CSB premix consisting of CSB plus sugar and oil (energy = 1231 kcal, MN = yes, duration = upon recovery)

    3. Concomitant interventions: extra MN, nutrition education, medical care

    4. Comparison: LNS full dose vs blended foods

  8. LNS (Plumpy'Doz), blended foods (CSB++)

    1. Intervention 1: LNS = Plumpy'Doz (energy = 270 kcal, MN = yes, duration = upon recovery)

    2. Intervention 2: blended food = CSB++ (energy = 273 kcal, MN = yes, duration = upon recovery)

    3. Intervention 3: children‐centred counselling using the “patient‐centredness model”

    4. Concomitant interventions: no

    5. Comparison: LNS complementary dose vs blended foods

Comments Information provided as (and if) reported in systematic review.

CSB: corn‐soy blend; CSB++: corn‐soy blend enriched; ID: identifier; kcal: kilocalories; LNS: lipid‐based nutrient supplement; MN: micronutrient; RUTF: ready‐to‐use therapeutic feeding.