NCT00797680.

Trial name or title	Duration of Hypothermia for Neuroprotection After Paediatric Cardiac Arrest
Methods	Randomized, open label, parallel assignment, safety and efficacy Phase II study
Participants	1 week ‐ 17 years  Chest compressions by a healthcare worker In‐hospital  and out‐of‐hospital arrest GCS  ≤ 8 PICU physician decision to use therapeutic hypothermia Central venous or arterial catheter in situ
Interventions	1) Therapeutic hypothermia: 72 hours at 33 ± 1ºC 2) Therapeutic hypothermia: 24 hours at 33 ± 1ºC
Outcomes	1) Degree of brain injury as measured by serum and urine biomarkers and magnetic resonance spectroscopy at hospital discharge  2 ) Frequency of adverse events at 30 days
Starting date	October 2008
Contact information	Dr Ericka Fink Children's Hospital of Pittsburgh, Pennsylvania, USA. finkel@ccm.upmc.edu
Notes	Planned enrolment 40 Planned end date April 2014