Gromert 2009.
Methods | Twelve‐month parallel‐group double‐blind placebo‐controlled randomised trial | |
Participants | Fifty children from 3 months to 4 years of age with moderate atopic dermatitis. No additional information provided on randomised numbers of participants in each arm | |
Interventions | Probiotic:Lactobacillus reuteri at a dose of 1 × 10⁸ CFUs/d taken orally suspended in 5 drops of food oil for 12 months Placebo: not specified but also given for 12 months |
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Outcomes | • SCORAD* • Subjective symptoms of atopic dermatitis: itching and loss of sleep* • Use of steroid treatment* *Denotes outcomes prespecified for this review |
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Notes | All available information taken from a conference abstract. No publication found, and study authors could not be contacted | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "In this prospective, double blind, randomised study..." Inadequate information: information on this study taken only from a conference abstract |
Allocation concealment (selection bias) | Unclear risk | Inadequate information: information on this study taken only from a conference abstract |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Quote: "In this prospective, double blind, randomised study..." Inadequate information: information on this study taken only from a conference abstract |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Quote: "In this prospective, double blind, randomised study..." Inadequate information: information on this study taken only from a conference abstract |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Inadequate information: information on this study taken only from a conference abstract |
Selective reporting (reporting bias) | Unclear risk | Inadequate information: information on this study taken only from a conference abstract |
Other bias | Unclear risk | Inadequate information: information on this study taken only from a conference abstract |