Skip to main content
. 2018 Nov 21;2018(11):CD006135. doi: 10.1002/14651858.CD006135.pub3

Gromert 2009.

Methods Twelve‐month parallel‐group double‐blind placebo‐controlled randomised trial
Participants Fifty children from 3 months to 4 years of age with moderate atopic dermatitis. No additional information provided on randomised numbers of participants in each arm
Interventions Probiotic:Lactobacillus reuteri at a dose of 1 × 10⁸ CFUs/d taken orally suspended in 5 drops of food oil for 12 months
Placebo: not specified but also given for 12 months
Outcomes • SCORAD*
• Subjective symptoms of atopic dermatitis: itching and loss of sleep*
• Use of steroid treatment*
*Denotes outcomes prespecified for this review
Notes All available information taken from a conference abstract. No publication found, and study authors could not be contacted
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "In this prospective, double blind, randomised study..."
Inadequate information: information on this study taken only from a conference abstract
Allocation concealment (selection bias) Unclear risk Inadequate information: information on this study taken only from a conference abstract
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Quote: "In this prospective, double blind, randomised study..."
Inadequate information: information on this study taken only from a conference abstract
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Quote: "In this prospective, double blind, randomised study..."
Inadequate information: information on this study taken only from a conference abstract
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Inadequate information: information on this study taken only from a conference abstract
Selective reporting (reporting bias) Unclear risk Inadequate information: information on this study taken only from a conference abstract
Other bias Unclear risk Inadequate information: information on this study taken only from a conference abstract