Summary of findings for the main comparison. Acellular dermal matrix graft (ADMG) + coronally advanced flap (CAF) compared to subepithelial connective tissue graft (SCTG) + CAF for treating adult patients with single recession‐type defects (short term).

ADMG + CAF compared to SCTG + CAF for adult patients with localised recession‐type defects (short term)
Patient or population: adult patients with single recession‐type defects Setting: university dental departments Intervention: ADMG + CAF Comparison: SCTG + CAF
Outcomes	Anticipated absolute effects* (95% CI)		Relative effect (95% CI)	Number of participants (studies)	Certainty of the evidence (GRADE)	Comments
	Risk with SCTG + CAF	Risk with ADMG + CAF
Aesthetic condition change related to patient's opinion	‐	‐	‐	‐	‐	Not reported
Sites with complete root coverage Follow‐up: range 6 months to 12 months	520 per 1000	245 per 1000 (123 to 597)	OR 0.43 (0.13 to 1.37)	50 (2 RCTs)	⊕⊕⊝⊝ LOW1	Only parallel‐design studies were included
Gingival recession change Follow‐up: range 6 months to 12 months	The mean gingival recession change ranged from 2.48 to 4.20 mm	MD 0.36 mm lower (1.03 lower to 0.3 higher)	‐	100 (4 RCTs)	⊕⊕⊝⊝ LOW2	Subgroup analyses were undertaken for parallel‐design and split‐mouth studies
Clinical attachment level change Follow‐up: range 6 months to 12 months	The mean clinical attachment level change ranged from 2.23 to 4.40 mm	MD 0.53 mm lower (1.14 lower to 0.08 higher)	‐	100 (4 RCTs)	⊕⊕⊝⊝ LOW2	Subgroup analyses were undertaken for parallel‐design and split‐mouth studies
Keratinized tissue change Follow‐up: range 6 months to 12 months	The mean keratinized tissue change ranged from ‐0.15 to ‐3.30 mm	MD 0.59 mm lower (1.27 lower to 0.10 higher)	‐	100 (4 RCTs)	⊕⊝⊝⊝ VERY LOW3	Subgroup analyses were undertaken for parallel‐design and split‐mouth studies.There was a clear inconsistence in the results according to the study design
*The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). ADMG: acellular dermal matrix graft; CAF: coronally advanced flap; CI: confidence interval; MD: mean difference; OR: odds ratio; RCT: randomised controlled trial; SCTG: subepithelial connective tissue graft.
GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect. Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect. Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.
1Downgraded 2 levels for imprecision. 2Downgraded 1 level for inconsistency and 1 for imprecision. 3Downgraded 2 levels for inconsistency and 1 for imprecision.