| EMP + CAF compared to CAF for adult patients with single recession‐type defects (short term) |
|
Patient or population: adult patients with single recession‐type defects
Setting: university/dental hospital
Intervention: EMP + CAF
Comparison: CAF |
| Outcomes |
Anticipated absolute effects* (95% CI) |
Relative effect
(95% CI) |
Number of participants
(studies) |
Certainty of the evidence
(GRADE) |
Comments |
| Risk with CAF |
Risk with EMP + CAF |
| Aesthetic condition change related to patient's opinion |
‐ |
‐ |
‐ |
‐ |
‐ |
Not reported |
| Gingival recession depth change
Follow‐up: range 6 months to 12 months |
The mean gingival recession depth change ranged from 2.16 to 3.80 mm |
MD 0.07 mm higher
(0.25 lower to 0.40 higher) |
‐ |
136
(3 RCTs) |
⊕⊕⊝⊝
LOW1
|
1 parallel‐design and 2 split‐mouth studies were included |
| Clinical attachment level change
Follow‐up: range 6 months to 12 months |
The mean clinical attachment level change ranged from 2.18 to 3.80 mm |
MD 0.22 mm higher
(0.02 lower to 0.45 higher) |
‐ |
136
(3 RCTs) |
⊕⊕⊝⊝
LOW1
|
1 parallel‐design and 2 split‐mouth studies were included |
| Keratinized tissue width change
Follow‐up: range 6 months to 12 months |
The mean keratinized tissue width change ranged from ‐0.30 to ‐0.53 mm |
MD 0.35 mm higher
(0.13 higher to 0.56 higher) |
‐ |
136
(3 RCTs) |
⊕⊕⊝⊝
LOW1
|
1 parallel‐design and 2 split‐mouth studies were included |
| *The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CAF: coronally advanced flap; CI: confidence interval; EMP: enamel matrix protein; MD: mean difference; RCT: randomised controlled trial. |
|
GRADE Working Group grades of evidence
High certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.
Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect. |
|
1Downgraded 1 level for inconsistency and 1 level for imprecision. |
