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. 2018 Oct 2;2018(10):CD007161. doi: 10.1002/14651858.CD007161.pub3

Leknes 2005.

Methods RCT, split‐mouth design, 2 treatment groups, 72 months' duration
Participants 20 individuals, 10 females, mean age 38.4 years, with 2 Miller Class I or II buccal gingival recessions of at least 3 mm. 11 individuals completed the study
Interventions 1. GTR (polylactic acid membrane ‐ Guidor)
2. CAF
Outcomes GRC
CALC
KTC
SCRC
PCRC
MRC
(Automated controlled force probe and manual probe)
Notes University/hospital‐based and membranes provided by Guidor AB
Unpublished data were included following contact with author
Data from earlier article (Amarante 2000) were reported as part of this trial
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Coin toss
Allocation concealment (selection bias) Unclear risk Method not reported
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Information not reported
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk All measurements were performed by 1 examiner not aware of the type of surgical procedure
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 11 out of 20 subjects were available for the final evaluation (6 subjects rejected to complete the study and 3 moved to other part of Norway)
 Data are equally missing in both intervention groups (split‐mouth design), but reasons for these are both reported and balanced across groups, then important bias is not expected
Selective reporting (reporting bias) Low risk Evidence of selective reporting of outcomes was not detected
Other bias Low risk Evidence of other was not detected