McGuire 2014.
Methods | RCT, split‐mouth design, 2 treatment groups, 5 years' duration | |
Participants | 30 individuals, 26 females, aged 18 to 70 years, with 2 Miller Class II buccal gingival recessions of at least 3 mm. 30 individuals completed the 6 months follow‐up, whereas 20 the 5 years follow‐up | |
Interventions | 1. Beta‐tricalcium phosphate (b‐TCP) + recombinant human platelet‐derived growth factor‐B with a bioabsorbable collagen wound‐healing dressing + CAF 2. SCTG + CAF |
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Outcomes | ACC GRC*(2) CALC KTC*(2) SCC PCRC MRC (Manual probe) |
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Notes | Practice‐based and supported by Osteohealth Unpublished data were included following contact with author |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Computer generated randomisation list |
Allocation concealment (selection bias) | Low risk | Adequate ‐ sealed envelope |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Information not reported |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | All measurements were performed by 1 examiner not aware of the type of surgical procedure |
Incomplete outcome data (attrition bias) All outcomes | Low risk | All patients completed the initial 6‐month evaluation, but 20 out 30 were available for follow‐up 5 years after the original recession‐related surgery (reasons were not reported) Data are equally missing in both intervention groups (split‐mouth design), but reasons for these are both reported and balanced across groups, then important bias is not to be expected |
Selective reporting (reporting bias) | Low risk | Evidence of selective reporting of outcomes was not detected |
Other bias | Low risk | Evidence of other bias was not detected |