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. 2018 Oct 2;2018(10):CD007161. doi: 10.1002/14651858.CD007161.pub3

Reino 2012.

Methods RCT, split‐mouth design, 2 treatment groups, 6 months' duration
Participants 12 individuals (heavy smokers ‐ 20 or more cigarettes per day for more than 5 years), 10 females, aged 35 to 50 years, with 2 bilateral Miller Class I or II buccal gingival recessions of at least 3 mm
Interventions 1. SCTG + CAF (extended flap)
2. SCTG + CAF
Outcomes SCRC
PCRC
MRC
(Automated controlled force probe and manual probe)
Notes University/hospital‐based and supported by the State of São Paulo Research Foundation, São Paulo, Brazil
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Coin toss
Allocation concealment (selection bias) Unclear risk Method not reported
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Information not reported
Blinding of outcome assessment (detection bias) 
 All outcomes High risk All measurements were performed by 1 examiner aware of the type of surgical procedure
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All patients completed the follow‐up period
Selective reporting (reporting bias) Unclear risk Baseline and follow‐up means regarding recession depth, clinical attachment level and keratinized tissue width were not reported in the study
Other bias Low risk Evidence of other bias was not detected