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. 2018 Oct 2;2018(10):CD007161. doi: 10.1002/14651858.CD007161.pub3

Trombelli 1996.

Methods RCT, split‐mouth design, 2 treatment groups, 6 months' duration
Participants 15 individuals, 3 female, aged 25 to 51 years, with 2 Miller Class I or II maxillary buccal gingival recessions of at least 3 mm
Interventions 1. CAF (fibrin glue + TTC‐HCl)
2. CAF (TTC‐HCl)
Outcomes GRC
CALC
KTC
SCRC
PCRC
MRC
(Manual probe)
Notes University/hospital‐based and supported by Italian Ministry of University and Scientific Research
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method not reported
Allocation concealment (selection bias) Unclear risk Method not reported
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Information not reported
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk All measurements were performed by 1 examiner not aware of the type of surgical procedure
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All patients completed the follow‐up period
Selective reporting (reporting bias) Low risk Evidence of selective reporting of outcomes was not detected
Other bias Low risk Evidence of other bias was not detected