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. 2018 Oct 2;2018(10):CD007161. doi: 10.1002/14651858.CD007161.pub3

Öncü 2017.

Methods RCT, split‐mouth design, 2 treatment groups, 6 months' duration
Participants 20 individuals, 11 females, age > 18 years, with maxillary bilateral multiple Miller Class I or II buccal gingival recession of at least 3 mm
Interventions 1. Platelet‐rich fibrin + CAF without vertical incisions
2. SCTG + CAF without vertical incisions
Outcomes GRC
CALC
KTC*(2)
SCRC
PCRC
MRC
(Manual probe)
Notes University/hospital‐based
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Coin toss
Allocation concealment (selection bias) Unclear risk Method not reported
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Patients remained unblinded to the root coverage procedure
Blinding of outcome assessment (detection bias) 
 All outcomes High risk All measurements were performed by 1 examiner aware of the type of surgical procedure
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All patients completed the follow‐up period
Selective reporting (reporting bias) Low risk Evidence of selective reporting of outcomes was not detected
Other bias Low risk Evidence of other bias was not detected

ACC: aesthetic condition change; ADMG: acellular dermal matrix graft; CA: citric acid; CAF: coronally advanced flap; CALC: clinical attachment change; DFDBA: demineralized freeze‐dried bone allograft; EMD: enamel matrix derivative; EMP: enamel matrix protein; ePTFE: expanded polytetrafluorethylene; FGG: free gingival graft; GRC: gingival recession change; GTR: guided tissue regeneration; KTC: keratinized tissue change; MRC: mean root coverage; PCRC: percentage of complete root coverage; RCT: randomised controlled trial; SCRC: sites with complete root coverage; SCTG: subepithelial connective tissue graft; TTC‐HCl: tetracycline hydrochloride; XCM ‐ xenogeneic collagen matrix. 
 *statistically significant between‐groups (superior group).