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. 2018 Nov 13;2018(11):CD010559. doi: 10.1002/14651858.CD010559.pub2

Chen 2015.

Methods Design: parallel RCT
Randomisation method: not reported
Blinding: no
Power calculation: no
Dropouts/withdrawals: no
Participants People with non‐small cell lung cancer who were receiving chemotherapy
Number (treatment/control): 72 (36/36)
Mean age (range): 58.53 (42‐72)
Gender (M/F): 43/29
Country: Shanghai city, China
Setting: hospital
Interventions Indirect moxa cone on ginger + conventional medicine vs conventional medicine
Treatment group
  • Indirect moxa cone

    • Indirect moxa cone on ginger placed on the acupoints ST36 zusanli) and RN12 (zhongwan) continuous 3 cones, once per day

    • Treatment duration: 10 days

  • Chemotherapy with docetaxel + cisplatin (TP)/gemcitabine + cisplatin (GP)/toxal + cisplatin (NP) for 8 days

  • Conventional treatment


Control group
  • Chemotherapy with TP/GP/NP for 8 days

  • Conventional treatment

  • Treatment duration: 10 days


Conventional treatment
  • Granisetron hydrochloride 3 mg and dexamethasone 5 mg, iv, 1/d

Outcomes FACT‐L4.0 (PWB) at the end of treatment
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk No relevant description
Incomplete outcome data (attrition bias) 
 All outcomes Low risk There was no loss to follow‐up. All participants were included in the analysis.
Selective reporting (reporting bias) Unclear risk Limited outcome measures were reported.
Other bias Unclear risk There was a statement about group similarity but without baseline characteristics data presented
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No blinding
Blinding of outcome assessment (detection bias) 
 Subjective outcomes High risk No blinding
Blinding of outcome assessment (detection bias) 
 Objective outcomes Unclear risk No objective outcome was reported.