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. 2018 Nov 13;2018(11):CD010559. doi: 10.1002/14651858.CD010559.pub2

Li 2012.

Methods Design: parallel RCT
Randomisation method: random number table
Blinding: no
Power calculation: no
Dropouts/withdrawals: no
Participants Cancer patients with leukopenia after having received chemotherapy
Number (treatment/control): 90 (60/30)
Mean age: 63.8
Gender (M/F): 53/37
Country: Henan province, China
Setting: hospital
Interventions Indirect moxa cone on ginger vs conventional medicine
Treatment group
  • Indirect moxa cone

    • Indirect moxa cone on ginger placed on the acupoints DU14 (dazhui), BL17 (geshu), BL20 (pishu) and BL21 (weishu) companied with other complementary acupoints, continuous 7 cones, once per day

    • Treatment duration: 9 days


Control group
  • conventional medicine

    • G‐CSF (recombinant human granulocyte colony‐stimulating factor injection), 100 µg, subcutaneous injection, once per day

    • Treatment duration: 7 days

Outcomes WBC count at the end of treatment and 8 days after the end of treatment
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random number table
Allocation concealment (selection bias) Unclear risk No relevant description
Incomplete outcome data (attrition bias) 
 All outcomes Low risk There was no loss to follow‐up. All participants were included in the analysis.
Selective reporting (reporting bias) Unclear risk Limited outcome measures were reported.
Other bias Unclear risk There was a statement about group similarity but without baseline characteristics data presented
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No blinding
Blinding of outcome assessment (detection bias) 
 Subjective outcomes Unclear risk No subjective outcome was reported.
Blinding of outcome assessment (detection bias) 
 Objective outcomes Low risk No blinding; however, machine‐measured objective outcomes were not influenced substantially