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. 2018 Nov 13;2018(11):CD010559. doi: 10.1002/14651858.CD010559.pub2

Liang 2002.

Methods Design: parallel RCT
Randomisation method: not reported
Blinding: no
Power calculation: no
Dropouts/withdrawals: no
Participants Cancer patients receiving chemotherapy
Number (treatment/control): 72 (36/36)
Mean age (range): not reported
Gender (M/F): not reported
Country: Shandong province, China
Setting: hospital
Interventions Moxa stick vs no treatment
Treatment group
  • Moxa stick

    • Moxa stick on the bilateral acupoints ST36 (zusanli) and RN12 (zhongwan), 15 minutes, once per day

    • Treatment duration: 14 days (beginning at the same day of chemotherapy)

  • Chemotherapy


Control group
  • Chemotherapy

Outcomes Leukocytes (WHO grade 3 to 4) at the end of treatment
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Unclear risk No relevant description
Incomplete outcome data (attrition bias) 
 All outcomes Low risk There was no loss to follow‐up. All participants were included in the analysis.
Selective reporting (reporting bias) Unclear risk Limited outcome measures were reported.
Other bias Unclear risk There was no statement about group similarity.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No blinding
Blinding of outcome assessment (detection bias) 
 Subjective outcomes Unclear risk No subjective outcome was reported.
Blinding of outcome assessment (detection bias) 
 Objective outcomes Low risk No blinding; however, machine‐measured objective outcomes were not influenced substantially