Yu 2004.

Methods	Design: parallel RCT Randomisation method: not reported Blinding: no Power calculation: no Dropouts/withdrawals: yes
Participants	The patients with cervical cancer (stage I, II and III) with Karnofsky score > 80 Number (treatment/control): 68 (38/30) Mean age (range): 58 (38‐81) Gender (M/F): F Country: Jiangsu province, China Setting: hospital
Interventions	Moxa stick vs no treatment Treatment group Moxa stick Moxa stick on RN8 (shenque), bilateral SP6 (sanyinjiao), and additional bilateral ST36 (zusanli) for those with syndrome of Qi deficiency, 10 minutes for each acupoint, once every other day Treatment duration: 8 weeks Radiotherapy Control group Radiotherapy
Outcomes	IgG, IgA, IgM, Hb, CD3, CD4, CD8 at the end of treatment
Notes	The studies Yu 2011, Yuan 2003, Yu 2002, Yu 2003a, Yu 2003b, Xu 2002, Xu 2003 and Zhu 2003 were considered to be reports of the same study as Yu 2004. The additional data from these studies were incorporated into Yu 2004.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Not described; there was an imbalance in the number of participants between groups
Allocation concealment (selection bias)	Unclear risk	No relevant description
Incomplete outcome data (attrition bias) All outcomes	High risk	There were participants lost to follow‐up.
Selective reporting (reporting bias)	Unclear risk	Limited outcome measures were reported.
Other bias	Unclear risk	It was mentioned that the groups were comparable, but no baseline characteristics data were presented.
Blinding of participants and personnel (performance bias) All outcomes	High risk	No blinding
Blinding of outcome assessment (detection bias) Subjective outcomes	Unclear risk	No subjective outcome was reported.
Blinding of outcome assessment (detection bias) Objective outcomes	Low risk	No blinding; however, machine‐measured objective outcomes were not influenced substantially