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. 2018 Nov 13;2018(11):CD010559. doi: 10.1002/14651858.CD010559.pub2

Zhang 2016a.

Methods Design: parallel RCT
Randomisation method: computer programme
Blinding: no
Power calculation: no
Dropouts/withdrawals: yes (2 in treatment group/3 in control group)
Participants People with non‐small cell lung cancer who had received chemotherapy after pulmonary lobectomy
Number (treatment/control): 70 (35/35)
Mean age: 55.55 (available participants)
Gender (M/F): 42/23 (available participants)
Country: Beijing city, China
Setting: hospital
Interventions Direct grain‐sized moxa cone vs no treatment
Treatment group
  • Direct grain‐sized moxa cone

    • Direct grain‐sized moxa cone on the bilateral acupoints ST36 (zusanli) and BL13 (feishu), continuous 9 cones, once per day

    • Treatment duration: 42 days


Control group
  • No treatment

Outcomes Platelet at the end of treatment
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer programme
Allocation concealment (selection bias) Unclear risk No relevant description
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk 2 participants dropped out in the treatment group and 3 in the control group.
Selective reporting (reporting bias) Unclear risk Limited outcome measures were reported.
Other bias Low risk Baseline characteristic data were comparable.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No blinding
Blinding of outcome assessment (detection bias) 
 Subjective outcomes Unclear risk No subjective outcome was reported.
Blinding of outcome assessment (detection bias) 
 Objective outcomes Low risk No blinding; however, machine‐measured objective outcomes were not influenced substantially