Zhang 2016b.

Methods	Design: parallel RCT Randomisation method: not reported Blinding: no Power calculation: no Dropouts/withdrawals: no
Participants	The patients with original non‐small cell lung cancer (stage IIIa, IIIb and IV) with expected survival time of > 3 months, Karnofsky > 60 Number (treatment/control): 60 (30/30) Mean age (range): 57.22 (42‐70) Gender (M/F): 31/29 Country: Guangdong province, China Setting: hospital
Interventions	Direct moxa cone + conventional medicine vs conventional medicine Treatment group Direct moxa cone Direct moxa cone on the acupoints sihua (bilateral BL17 (geshu) and BL19 (danshu)), continuous 3 cones, once per day Treatment duration: 10 days Conventional medicine Symptomatic treatment including granisetron and dexamethasone Chemotherapy with paclitaxel and cisplatin Control group Conventional medicine Symptomatic treatment including granisetron and dexamethasone Chemotherapy with paclitaxel and cisplatin
Outcomes	FACT‐L, Karnofsky score, nausea/vomiting (WHO grade 3 to 4) at the end of treatment
Notes	—
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	No relevant description
Incomplete outcome data (attrition bias) All outcomes	Low risk	There was no loss to follow‐up. All participants were included in the analysis.
Selective reporting (reporting bias)	Unclear risk	Limited outcome measures were reported.
Other bias	Unclear risk	It was mentioned that the groups were comparable, but no baseline characteristics data were presented.
Blinding of participants and personnel (performance bias) All outcomes	High risk	No blinding
Blinding of outcome assessment (detection bias) Subjective outcomes	High risk	No blinding
Blinding of outcome assessment (detection bias) Objective outcomes	Unclear risk	No objective outcome was reported.