| Methods |
Randomized, double blinded, placebo‐controlled trial |
| Participants |
ARDS |
| Interventions |
iv N‐acetylcysteine 150 mg/kg bolus and 20 mg/kg/hr for 7 days versus placebo (not stated) |
| Outcomes |
resolution of ARDS |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Only stated: patients were randomized. |
| Allocation concealment (selection bias) |
Unclear risk |
Not stated. |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
Patients and staff were blinded for treatment allocation. |
| Selective reporting (reporting bias) |
Low risk |
|
| Other bias |
Low risk |
|
