Summary of findings 15. HP paint‐on gel versus HP strips for whitening teeth.
| Hydrogen peroxide (HP) paint‐on gel compared to HP strips for whitening teeth | ||||||
| Patient or population: adults undergoing bleaching Setting: home‐based Intervention: HP paint‐on Comparison: HP strips | ||||||
| Tooth whitening ‐ assessed by the dentist | ||||||
| Comparisons | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | Number of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
| Risk with 5.9% HP paint‐on | Risk with 5.9% HP strip | |||||
| 5.9% HP paint‐on versus 5.9% HP strip (higher shade indicates whiter) | ‐ | Mean difference in 5.90% HP strip group was 2.70 higher (2.08 higher to 3.32 higher) | ‐ | 40 (1 RCT) | ⊕⊝⊝⊝ VERY LOW1, 2 | ‐ |
| Tooth whitening ‐ reported by the patient | ||||||
| 5.9% HP paint‐on versus 5.9% HP strip (higher shade indicates whiter) | The mean patient satisfaction for 5.90% HP paint on gel group was ‐4 | Mean difference in patient satisfaction was 0.25 lower for 5.90% HP strip group (1.88 lower to 1.38 higher) | ‐ | 40 (1 RCT) | ⊕⊝⊝⊝ VERY LOW1, 2 | |
| Adverse effects | ||||||
| Adverse events were mild in severity, and did not contribute to any treatment modification or early withdrawal. Slightly higher tooth hypersensitivity and gingival irritation in the strip group was found although there was no evidence of a difference between the groups | ||||||
| *The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI) CI: confidence interval; RCT: randomised controlled trial | ||||||
| GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect | ||||||
1Downgraded for risk of bias ‐ unclear risk of bias due to lack of selection, performance and detection bias. 2Downgraded for imprecision ‐ single trial, low sample and event rate.