Summary of findings 18. HP paint‐on versus HP paint‐on for whitening teeth.
| Hydrogen peroxide (HP) paint‐on compared to HP paint‐on for whitening teeth | ||||||
| Patient or population: adults undergoing bleaching Setting: home‐based Intervention: HP paint‐on Comparison: HP paint‐on | ||||||
| Tooth whitening ‐ assessed by the dentist | ||||||
| Comparison | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | Number of participants (studies) | Certainty of the evidence (GRADE) | Comments | |
| Risk with 6% HP paint‐on | Risk with 6% HP paint‐on with KF | |||||
| 6% HP paint‐on versus 6% HP paint‐on with KF (higher shade indicates whiter) | The mean shade change in the 6% HP paint‐on group was 2.70 | Mean difference in shade change was 0.10 lower in 6% HP paint‐on with KF (0.56 lower to 0.36 higher) | ‐ | 67 (1 RCT) | ⊕⊝⊝⊝ VERY LOW1, 2 | ‐ |
| Adverse effects | ||||||
| Tooth sensitivity was noted in both groups with no evidence of a difference | ||||||
| *The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI) CI: confidence interval; KF: potassium fluoride; RCT: randomised controlled trial | ||||||
| GRADE Working Group grades of evidence High certainty: we are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect | ||||||
1Downgraded for risk of bias ‐ unclear risk of bias due to lack of selection, performance and detection bias. 2Downgraded for imprecision ‐ single trial, low sample and event rate.