Mostajeran 2017.
| Methods | Design: 2‐arm parallel RCT | |
| Participants |
Number: 100 Women's age: mean 31.3 ± 5.2 years Inclusion criteria: women 20 to 40 years old with body mass index 18 to 30 kg/m² were eligible if they were infertile owing to male factor, had a regular menstrual cycle of 24 to 35 days, and were presumed to be ovulatory Exclusion criteria: presence of polycystic ovary syndrome, with uterine pathologies, endometriosis, or presence of hydrosalpinges and any endocrine disease or chronic systemic illness; azoospermia; history of successful IVF or ICSI Ovarian controlled hyperstimulation: not mentioned Fertilisation: IVF and ICSI Stage of the embryo at transfer: blastocyst Embryo processing: frozen/thawed Number of embryos transferred: 1 to 3 |
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| Interventions |
Experimental (n = 50): injection of 700 IU of intrauterine hCG (chorionic gonadotropin human, Darou Pakhsh Company, Iran) 10 minutes before embryo transfer Control (n = 50): did not receive hCG before embryo transfer |
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| Outcomes | Clinical pregnancy | |
| Notes |
Location: Fertility and Infertility Center of Isfahan in Iran Period: September 2013 to April 2014 Power calculation: yes, but inadequate Funding: not mentioned Trial registration: not mentioned Publication type: full text |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | Participants were randomly divided into two 50‑member groups by random allocation software. Saghaei, 2004 |
| Allocation concealment (selection bias) | Unclear risk | Not mentioned |
| Blinding of participants and personnel (performance bias) All outcomes | Low risk | Embryo transfer in both groups was done by the attending gynaecologist, who was blinded to the study. |
| Blinding of outcome assessment (detection bias) All outcomes | Low risk | Not blinded, but unlikely to induce bias |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | 6 participants lost to follow‐up |
| Selective reporting (reporting bias) | Unclear risk | No data on miscarriage or live birth |
| Other bias | Low risk | Similar baseline characteristics between groups after randomisation |