Comparison 6. Alcohol, tobacco, and/or drug use.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Composite Substance Use (short‐term)	7		Odds Ratio (Random, 95% CI)	Subtotals only
1.1 Family Targeted	2	213	Odds Ratio (Random, 95% CI)	0.81 [0.50, 1.33]
1.2 School Targeted	2	342	Odds Ratio (Random, 95% CI)	0.55 [0.24, 1.25]
1.3 School Universal	3	7390	Odds Ratio (Random, 95% CI)	1.03 [0.77, 1.37]
2 Composite Substance Use (long‐term)	6		Odds Ratio (Random, 95% CI)	Subtotals only
2.1 Family Targeted	4	1622	Odds Ratio (Random, 95% CI)	0.69 [0.47, 1.03]
2.2 School Universal	2	2145	Odds Ratio (Random, 95% CI)	1.09 [0.94, 1.27]