Patient is able to undergo the vertebroplasty or balloon kyphoplasty procedure
Patient has read and signed informed consent
Male or female, 50 years or older
One or two non‐traumatic vertebral fracture(s) between T5 and L5
Of osteoporotic origin (low‐speed trauma such as fall from his own height or less than 80 cm)
Fracture(s) older than 6 weeks duration after the onset of pain related to the fracture and fracture(s) exhibit(s) high signal intensity on T2‐weighted images and a benign appearance at MRI
Persistent pain despite medical treatment according to VAS = 5 or a last resort to morphine treatment
The patient will be able to receive the selected protocol treatment within 15 days after treatment randomisation.
The benign nature of the vertebral fracture has to be confirmed by the results of the biopsy performed during vertebroplasty or balloon kyphoplasty.
Patient with a vertebral fracture of less than 6 weeks duration after onset of fracture‐related symptoms.
Neurological signs related to the vertebral fracture to treat
History of surgical or percutaneous spine treatment except simple discectomy at a single or multiple vertebral levels with no residual pain
Patient with more than 2 fractures corresponding to the inclusion criteria (old fractures are not taken into account)
More than two recent vertebral fractures
Current infection
Impossibility to perform the percutaneous approach of the vertebra to treat.
Reduction by more than 50% of the anteroposterior width of the bony spinal canal due to the vertebral fracture to treat.
Known allergy to a contrast media or to one of the cement components used for kyphoplasty.
Vertebral fracture with loss of 90% or more of the vertebral body height
Neurological signs or symptoms related to the vertebral fracture
Malignant and traumatic vertebral fractures
Contraindication to MRI: Metallic implant (pace‐maker, non AMOVIBLE auditive implant, metallic vascular or cardiac device; metallic surgical clips; claustrophobia
Evolutive cardiac disease non reactive to medical treatment
Patient presenting a non correctable spontaneous or therapeutic coagulation disorder.
Presence of an unexplained biological inflammatory syndrome with NFS = 20
Noncompliant patient: Impossibility to participate to the study and to be followed up for 1 year.
Pregnant or breast feeding women
Patient not affiliated to social security
