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. 2018 Nov 30;2018(11):CD003177. doi: 10.1002/14651858.CD003177.pub4

AC Omega3 2014.

Trial name or title Aboriginal Cardiovascular Omega‐3 randomised controlled trial (AC Omega3)
Methods RCT
Participants Indigenous Australian adults with stable coronary artery disease
Interventions Each for 12 months:
Arm 1: omega‐3 (1800 mg/d AlaskOmega: 3 capsules/d: 400 mg EPA and 200 mg DHA)
Arm 2: placebo mixed oil capsules (1000 mg/d: 3 capsules/d containing palm oil, gelatin, glycerol, sunflower oil, rapeseed oil, mixed tocopherols, and a "small amount" of fish oil (for taste to aid blinding)
Outcomes Primary: serum non‐HDL‐C
Secondary: triglycerides, total cholesterol, LDL cholesterol, HDL cholesterol, lipid functionality by cholesterol efflux and CETP, heart rate variability, platelet function and thrombosis markers, inflammation markers, cumulative combined rate of major adverse cardiac events (including death, non‐fatal MI, unstable angina, non‐fatal stroke, revascularisation and cardiac related hospital admissions)
Starting date Registered on trials registry: 10 July 2014
Study start date: 1 October 2014
Estimated study completion date: unclear
Contact information Alex Brown (PI), Wardliparingga Aboriginal Unit, Adelaide, Australia, alex.brown@sahmri.com
Notes ACTRN12614000732684
Alex Brown contacted in 2016: confirmed study is actively recruiting
HHS Vulnerability Disclosure