AC Omega3 2014.
Trial name or title | Aboriginal Cardiovascular Omega‐3 randomised controlled trial (AC Omega3) |
Methods | RCT |
Participants | Indigenous Australian adults with stable coronary artery disease |
Interventions | Each for 12 months: Arm 1: omega‐3 (1800 mg/d AlaskOmega: 3 capsules/d: 400 mg EPA and 200 mg DHA) Arm 2: placebo mixed oil capsules (1000 mg/d: 3 capsules/d containing palm oil, gelatin, glycerol, sunflower oil, rapeseed oil, mixed tocopherols, and a "small amount" of fish oil (for taste to aid blinding) |
Outcomes | Primary: serum non‐HDL‐C Secondary: triglycerides, total cholesterol, LDL cholesterol, HDL cholesterol, lipid functionality by cholesterol efflux and CETP, heart rate variability, platelet function and thrombosis markers, inflammation markers, cumulative combined rate of major adverse cardiac events (including death, non‐fatal MI, unstable angina, non‐fatal stroke, revascularisation and cardiac related hospital admissions) |
Starting date | Registered on trials registry: 10 July 2014 Study start date: 1 October 2014 Estimated study completion date: unclear |
Contact information | Alex Brown (PI), Wardliparingga Aboriginal Unit, Adelaide, Australia, alex.brown@sahmri.com |
Notes | ACTRN12614000732684 Alex Brown contacted in 2016: confirmed study is actively recruiting |