REDUCE‐IT 2011.

Trial name or title	Reduction of cardiovascular events with EPA‐intervention trial (REDUCE‐IT)
Methods	RCT
Participants	Patients (45 years or over) with hypertriglyceridaemia, with cardiovascular disease or at high risk for cardiovascular disease, and on statin
Interventions	Each for 4‐6 years: Arm 1: EPA ethyl ester (AMR101 4 g/d) Arm 2: placebo
Outcomes	Primary: composite of cardiovascular death, MI, stroke, coronary revascularisation and hospitalisation for unstable angina Secondary: incidence of additional cardiovascular events, lipid and lipoprotein levels
Starting date	Registered on trials registry: 13 December 2011 Study start date: November 2011 Estimated study completion date: December 2017
Contact information	Deepak Bhatt (PI), Brigham and Women's Hospital
Notes	NCT01492361