Table 4.

Performance (F1-score) changes for the selected GO terms after the enrichment of training datasets with electronic annotations. In this analysis, the training was done using all of the available annotations, without any selection based on the evidence code.

	GO Term	GO Description	NoA* (ME*)	NoA (AE*)	F1-score perf. (ME)	F1-score perf. (AE)	Perf. Change
Previously low performance models	GO:0070569	uridylyltransferase activity	35	970	0.58	0.88	0.30
	GO:0019203	carbohydrate phosphatase activity	63	681	0.51	0.84	0.33
	GO:0004197	cysteine-type endopeptidase activity	100	853	0.45	0.40	-0.05
	GO:0005524	ATP binding	596	85 442	0.53	0.93	0.40
	GO:0030554	adenyl nucleotide binding	689	86 319	0.51	0.90	0.39
	GO:0035639	purine ribonucleoside triphosphate binding	834	98 924	0.43	0.80	0.37
	GO:0032555	purine ribonucleotide binding	951	99 286	0.51	0.89	0.38
	GO:0097367	carbohydrate derivative binding	1 395	10 413	0.41	0.73	0.32
	GO:0000166	nucleotide binding	1 487	116 408	0,53	0.82	0.29
	GO:0036094	small molecule binding	2 059	12 634	0.40	0.72	032
	GO:0043169	cation binding	2 145	119 698	0.48	0.71	0.23
	GO:0043167	ion binding	4 132	20 278	0.33	0.79	0.46
Previously high performance models	GO:0004784	superoxide dismutase activity	38	459	0.81	0.68	-0.13
	GO:0004004	ATP-dependent RNA helicase activity	48	954	0.75	0.73	-0.02
	GO:0005525	GTP binding	258	14 479	0.95	0.79	-0.16
	GO:0032550	purine ribonucleoside binding	286	14 496	0.89	0.62	-0.27
	GO:0001883	purine nucleoside binding	289	14 506	0.89	0.87	-0.02
	GO:0032549	ribonucleoside binding	296	15 460	0.78	0.80	0.02
	GO:0001882	nucleoside binding	304	15 508	0.92	0.79	-0.13
	GO:0008270	zinc ion binding	520	11 385	0.83	0.71	-0.12
	GO:0032559	adenyl ribonucleotide binding	673	85 691	0.80	0.80	0.00
	GO:0017076	purine nucleotide binding	975	99 924	0.91	0.65	-0.26
	GO:0032553	ribonucleotide binding	1 025	100 844	0.87	0.61	-0.26
	GO:0046872	metal ion binding	1 985	118 577	0.81	0.80	-0.01
	GO:0004784	superoxide dismutase activity	38	459	0.81	0.68	-0.13
	Average		861	47 658	0.68	0.77	0.10

*NoA: Number of Annotations, ME: Manual-Experimental Evidence, AE: All Evidence.