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. 2019 May 14;9:7355. doi: 10.1038/s41598-019-43782-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Kaplan-Meier survival curves from the diagnosis of interstitial pneumonia (IP), according to indicated clinical factors in patients with systemic lupus erythematosus (SLE)-related IP. (A) Current smokers (log-rank, p = 0.0001), (C) patients with thrombocytopenia (log-rank, p = 0.036), and (F) patients with high extent of lung fibrosis (extent scores of 2 or 3) on HRCT (log-rank, p = 0.002) showed significantly worse prognoses than those without these characteristics. (B) Absence of comorbid other connective tissue diseases (CTDs) (log-rank, p = 0.051) and (D) low anti-dsDNA antibody titre (<34.4 based on median value, log-rank, p = 0.093) were not significantly related with prognosis. E, Activity of SLE (SLEDAI-2K score) was not associated with prognosis either (≥12 based on median value, log-rank, p = 0.750).