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. 2019 May 14;10:2060. doi: 10.1038/s41467-019-10004-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Chemical structure and mechanical properties of the hydrogels. a Constituent chemical structures and a schematic diagram illustrating the formation of the photo-triggered imine-crosslinked matrix hydrogel. b To monitor the gelling process, a dynamic time-sweep rheological analysis was carried out with an in situ photo-rheometer (HAAKE Mars III, light, Omnicure S2000 365 nm: 30 mW cm⁻²) showing the formation kinetics for GelMA/HA-NB/LAP, GelMA/HA-NB, and GelMA/LAP hydrogels. c The final torsion modulus G’ of different hydrogels. d The gel point of different hydrogels. All the gelling measurements were conducted using OmniCure S2000 (365 nm, 30 mW/cm²). Exposure time: 180 s for GelMA/HA-NB/LAP and GelMA hydrogels, and 300s for GelMA/HA-NB hydrogel (error bars, mean ± SD. ****p < 0.0001; NS: no significance, one-way analysis of variance (ANOVA), Tukey’s post hoc test) (n = 3 per group). Source data are available in the Source Data file