Table 2.

Main anti-tumoral studies carried out in vitro and in vivo with MC components.

Tumor	Compound(s)	Cells	Animals	References
Breast	Cucurbitane-type triterpene	MCF-7, MDA-MB-231		Weng et al., 2013
	RNase MC2	MCF-7		Fang et al., 2012a
	MC extract	MCF-7, MDA-MB-231		Ray et al., 2010
	Eleostearic acid	MDA-ERα7		Grossmann et al., 2009
	Water MC extract		SHN mice	Nagasawa et al., 2002
	MAP30	MDA-MB-231	SCID mice	Lee-Huang et al., 2000
	α-momorcharin	MCF-7, MDA-MB-231, MDAMB-453	Balb/C mice	Cao et al., 2015
Colon	Methanol MC extract	HT-29, SW480, HFF		Kwatra et al., 2013
	Methanol MC extract	Hone-1, AGS, HCT-116, CL1-0		Li et al., 2012a
	Acid and alkali MC extracts	SGC-7901		Li et al., 2012b
	MAP30	LoVo		Fan et al., 2008
	MC fatty acids	Caco-2		Yasui et al., 2005
	MC extract		Swiss mice	Deep et al., 2004
	MC extract		F344 rats	Kohno et al., 2004
Liver	MAP30	Hep G2	Balb/C nude mice	Fang et al., 2012b
	RNase MC2	Hep G2	Balb/C nude mice	Fang et al., 2012c
	MC lectin	Hep G2, PLC/PRF/5	Nude mice	Zhang et al., 2015
	Cucurbitane-type triterpene glycosides	Hep G2, Hep 3B		Yue et al., 2019
Prostate	MC extract	PC3, LNCaP	TRAMP mice	Ru et al., 2011
	MC leaf extract, Kuguacin J	LNCaP, PNT1A		Pitchakarn et al., 2011
	MC leaf extract	PLS10	Nude mice	Pitchakarn et al., 2010
	MCP30	LNCaP, PC-3, RWPE-1, PIN	Nude mice	Xiong et al., 2009
Bladder	48–127/momordin IT	T24		Battelli et al., 1996
Glioma	Transferrin/momordin IT	HS683, U251		Gosselaar et al., 2002
Lymphoma	Ber-H2/momordin IT	ALCL	SCID mice	Terenzi et al., 1996
	OM124/momordin IT	Daudi, EHM, BJAB, Raji, BM21	SCID mice	Bolognesi et al., 1998
Leukemia	Ethanol MC extracts	ED, Su9T01, S1T, HUT-102, MT-2, Jurkat, MOLT-4		Kai et al., 2011
	Ethanol MC extracts	HL60	Balb/cAnNCrj-nu/nu mice	Kobori et al., 2008b
	Anti-CD5/momordin IT	Peripheral blood mononuclear cells, Jurkat	nu/nu mice	Porro et al., 1993