Table 1.

Quality assessment.

References	Q1	Q2	Q3	Q4	Q5	Q6	Q7	Q8	Q9	Q10	Score
Liang et al., 2002	✓		✓				✓				3
Liang et al., 2003	✓		✓				✓		✓		4
Park et al., 2003	✓	✓	✓			✓	✓		✓		6
Kim et al., 2005	✓	✓	✓				✓				4
Kang et al., 2007	✓		✓				✓				3
Jeon et al., 2008	✓		✓				✓		✓	✓	5
Choi et al., 2009	✓		✓				✓				3
Jia et al., 2009	✓		✓			✓	✓				4
Hong et al., 2010	✓	✓	✓						✓		4
Jia et al., 2010	✓		✓						✓		3
Kim et al., 2010	✓		✓						✓		3
Yu et al., 2010	✓	✓	✓			✓	✓		✓		6
Choi et al., 2011a	✓		✓				✓		✓		4
Choi et al., 2011b	✓		✓				✓		✓		4
Kim et al., 2011a	✓		✓			✓			✓	✓	5
Kim et al., 2011b	✓		✓			✓			✓	✓	5
Wang et al., 2011	✓	✓	✓			✓			✓	✓	6
Yeo et al., 2013	✓		✓				✓		✓	✓	5
Huo et al., 2012	✓		✓			✓	✓		✓	✓	6
Sun et al., 2012	✓		✓			✓	✓		✓		5
Rui et al., 2013	✓	✓	✓			✓	✓		✓		6
Wang et al., 2013	✓	✓	✓			✓			✓		5
Yu et al., 2016	✓		✓			✓	✓		✓		5
Kim et al., 2014	✓		✓			✓	✓		✓		5
Deng et al., 2015	✓		✓				✓		✓	✓	5
Lv et al., 2015	✓		✓			✓	✓		✓	✓	6
Park et al., 2015	✓	✓	✓						✓	✓	5
Shen et al., 2015	✓		✓						✓	✓	4
Yeo et al., 2015	✓		✓						✓		3
Jia et al., 2017	✓		✓			✓	✓		✓	✓	6
Sun et al., 2016	✓	✓	✓			✓	✓		✓	✓	7
Tian et al., 2016	✓		✓								2
Yang et al., 2011	✓	✓	✓				✓		✓	✓	6
Yang et al., 2017	✓	✓	✓			✓	✓		✓	✓	6
Park et al., 2017	✓	✓	✓			✓			✓	✓	6
Jeon et al., 2017	✓	✓	✓						✓	✓	5
Lee et al., 2018	✓	✓	✓						✓	✓	5
Lu et al., 2017	✓	✓	✓				✓		✓	✓	6
Li et al., 2017a	✓		✓								2
Li et al., 2017b	✓		✓								2
Lin et al., 2017	✓		✓						✓	✓	4
Wang et al., 2018	✓		✓				✓		✓	✓	5

Q1, publication in a peer-reviewed journal; Q2, statements describing control of temperature; Q3, random allocation to treatment or control; Q4, blinded building of model; Q5, use of aged animal model; Q6, blinded assessment of outcome; Q7, use of anesthetic without significant intrinsic neuroprotective activity; Q8, sample size calculation; Q9, compliance with animal welfare regulations; Q10, declared any potential conflict of interest.