Table 3.

ART outcomes in “suboptimal” responder women.

Variable	FSH	hMG	FSH+LH	p-value
Number of cycles n (%)	2,715 (71.0%)	514 (13.4%)	593 (15.5%)
Female Age (years)	37.09 ± 3.84	38.41 ± 3.50	38.68 ± 3.18	<0.001
Male Age (years)	39.62 ± 5.40	40.65 ± 5.20	40.88 ± 45.07	<0.001
Basal FSH (IU/L)	7.62 ± 2.88	8.07 ± 3.26	8.67 ± 3.53	<0.001
Basal LH (IU/L)	5.90 ± 9.53	5.22 ± 5.24	5.55 ± 4.04	0.674
AMH (ng/mL)	1.77 ± 1.66	1.25 ± 1.23	1.10 ± 1.12	<0.001
AFC	8.74 ± 6.15	6.73 ± 3.88	5.84 ± 3.28	<0.001
Total FSH doses (IU/L)	3,187 ± 1,312	3,559 ± 1,225	3,197 ± 1,028	<0.001
Total LH dose (IU/L)	0	0	1,401 ± 556	<0.001
FSH dose/oocytes ratio	536 ± 303	644 ± 319	583 ± 249	<0.001
Oocytes retrieved	6.56 ± 1.67	6.04 ± 1.62	5.92 ± 1.59	<0.001
MII oocytes	4.90 ± 1.85	4.51 ± 1.69	4.47 ± 1.63	<0.001
MII oocytes/oocytes retrieved	0.75 ± 0.21	0.75 ± 0.22	0.76 ± 0.21	0.314
Injected oocytes	4.77 ± 1.86	4.46 ± 1.71	4.37 ± 1.65	<0.001
Frozen oocytes	0.05 ± 0.50	0.04 ± 0.40	0.05 ± 0.47	0.844
Fertilized oocytes	3.42 ± 1.83	3.22 ± 1.63	3.04 ± 1.65	<0.001
Cumulative embryos	2.36 ± 1.12	2.35 ± 1.02	2.29 ± 1.06	0.316
Transferred embryos	1.99 ± 0.89	2.09 ± 0.87	2.07 ± 0.95	0.017
Frozen embryos	0.38 ± 0.83	0.27 ± 0.67	0.22 ± 0.60	0.072
Implantation rate	13.89 ± 27.69	12.97 ± 26.70	10.86 ± 24.33	0.060
Biochemical pregnancies n (%)	598 (22.0%)	109 (21.2%)	110 (18.5%)	0.170
Deliveries n (%)	437 (16.1%)	79 (15.4%)	81 (13.7%)	0.981
Miscarriage n (%)*	150 (5.5%)	27 (5.2%)	27 (4.5%)	0.962
Miscarriage n (%)**	150 (25.1%)	27 (24.8%)	27 (24.5%)
Ectopic pregnancies n (%)*	10 (0.4%)	3 (0.6%)	2 (0.3%)	0.941
Ectopic pregnancies n (%)**	10 (1.7%)	3 (2.7%)	2 (1.8%)

Data are expressed as mean ± standard deviation or number (percentage).

^*% Considering the total number of cycles.

^**% Considering the number of clinical pregnancies.

Bold values, represent statistical significant p-values.