Figure 4.
ECM remodeling molecular response to a pro-inflammatory stimulus. Expression of metalloproteases (MMP1, MMP3, MMP13) (A) and their inhibitors (TIMP1, TIMP3) (B) in adipose (ASCs)-, bone marrow (BMSCs)-derived MSCs, and cartilage cells (CCs) obtained from the same donors, assessed by quantitative real-time PCR at P3 before and after IL-1β stimulation. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. ASCs, § p < 0.05, §§ p < 0.01, §§§ p < 0.001 vs. BMSCs, ° p < 0.05, °° p < 0.01 vs. control. Data are expressed as mean ± SD (n = 8).