. 2019 Apr 23;8(4):139. doi: 10.3390/foods8040139

Table 2.

Anticancer activities of rhus and safflower extracts and their nanoparticles against Caco-2, HEPG2 and T47D cell lines.

Samples	Conc. (µg mL⁻¹)	Cancer Cell Inhibition %			IC₅₀ (µg mL⁻¹)
Samples	Conc. (µg mL⁻¹)	Caco	HEPG2	T47D	Caco	HEPG2	T47D
Rhus Extract	100	6.28 ± 0.53 ^p*	10.34 ± 0.87 ^s	17.71 ± 1.23 ^p	1405.67 ± 17.14 ^a	1093.46 ± 11.37 ^a	1055.24 ± 12.27 ^a
Rhus Extract	250	12.24 ± 1.10 ^mn	15.23 ± 0.74 ^r	22.37 ± 0.92 ^o
Rhus Extract	500	19.72 ± 1.37 ^l	26.98 ± 1.13 ^o	30.72 ± 1.45 ^m
Rhus + AgNPs	100	7.97 ± 0.82 ^op	23.77 ± 0.81 ^p	24.22 ± 1.11 ^o	1147.89 ± 13.75 ^b	720.49 ± 9.89 ^b	567.38 ± 9.14 ^e
Rhus + AgNPs	250	11.17 ± 0.98 ⁿ	32.32 ± 1.91 ^m	29.33 ± 1.87 ^mn
Rhus + AgNPs	500	23.99 ± 1.47 ^k	46.20 ± 2.50 ⁱ	40.94 ± 2.12 ^l
Rhus + ZnNPs	100	9.04 ± 0.70 ^o	30.18 ± 1.35 ⁿ	27.47 ± 1.76 ⁿ	1005.16 ± 10.52 ^e	676.17 ± 8.21 ^c	538.07 ± 10.78 ^d
Rhus + ZnNPs	250	13.31 ± 0.96 ^mn	36.59 ± 1.81 ^hl	32.12 ± 1.30 ^m
Rhus + ZnNPs	500	27.19 ± 1.10 ^j	48.34 ± 1.57 ^h	43.26 ± 2.04 ^l
Rhus + CuNPs	100	18.65 ± 0.93 ^l	66.49 ± 2.72 ^d	47.44 ± 2.73 ^k	721.91 ± 9.89 ^e	169.52 ± 5.53 ^f	3.58 ± 0.06 ⁱ
Rhus + CuNPs	250	25.06 ± 1.23 ^jk	71.83 ± 3.14 ^c	52.55 ± 2.81 ^j
Rhus + CuNPs	500	38.94 ± 1.51 ^g	91.06 ± 4.26 ^b	66.94 ± 3.12 ^g
Rhus + FeNPs	100	5.83 ± 0.27 ^p	35.52 ± 1.41 ^l	31.19 ± 2.02 ^m	926.05 ± 11.31 ^d	443.45 ± 9.25 ^d	342.33 ± 9.43 ^h
Rhus + FeNPs	250	14.38 ± 0.81 ^m	45.13 ± 1.84 ^ij	40.94 ± 1.90 ^l
Rhus + FeNPs	500	27.19 ± 1.09 ^j	59.02 ± 2.08 ^e	52.55 ± 2.71 ^j
Safflower Extract	100	24.84 ± 1.19 ^jk	14.38 ± 0.82 ^r	44.34 ± 2.23 ^l	615.77 ± 7.43 ^f	202.29 ± 5.35 ^e	707.75 ± 10.10 ^b
Safflower Extract	250	32.27 ± 1.32 ⁱ	22.92 ± 1.07 ^p	52.88 ± 1.84 ^j
Safflower Extract	500	44.34 ± 1.56 ^e	37.87 ± 0.91 ^k	65.70 ± 3.16 ^g
Safflower + AgNPs	100	37.84 ± 1.22 ^gh	30.40 ± 1.12 ⁿ	58.22 ± 2.40 ⁱ	282.09 ± 8.51 ^h	18.24 ± 0.80 ^h	359.21 ± 9.71 ^g
Safflower + AgNPs	250	49.91 ± 1.74 ^d	44.28 ± 1.64 ^j	72.11 ± 3.21 ^f
Safflower + AgNPs	500	62.45 ± 1.85 ^c	59.23 ± 2.04 ^e	85.99 ± 3.80 ^d
Safflower + ZnNPs	100	41.09 ± 1.31 ^f	33.60 ± 1.83 ^m	62.49 ± 2.70 ^h	261.52 ± 7.27 ⁱ	7.18 ± 0.67 ⁱ	386.49 ± 7.61 ^f
Safflower + ZnNPs	250	49.91 ± 1.87 ^d	45.35 ± 2.32 ^ij	71.04 ± 3.01 ^f
Safflower + ZnNPs	500	62.45 ± 2.23 ^c	54.96 ± 1.95 ^f	90.26 ± 3.83 ^e
Safflower + CuNPs	100	65.23 ± 1.92 ^b	67.78 ± 2.27 ^d	83.85 ± 2.94 ^d	3.12 ± 0.81 ^j	1.11 ± 0.04 ^j	1.42 ± 0.07 ^j
Safflower + CuNPs	250	66.77 ± 2.34 ^b	70.98 ± 2.70 ^c	93.47 ± 3.52 ^b
Safflower + CuNPs	500	89.33 ± 3.28 ^a	97.68 ± 3.44 ^a	98.94 ± 4.03 ^a
Safflower + FeNPs	100	26.23 ± 1.27 ^jk	19.72 ± 0.98 ^q	48.61 ± 2.81 ^k	498.32 ± 9.34 ^g	99.61 ± 8.72 ^g	487.45 ± 8.48 ^e
Safflower + FeNPs	250	35.98 ± 1.81 ^h	32.53 ± 1.23 ^m	62.49 ± 0.87 ^h
Safflower + FeNPs	500	49.91 ± 2.09 ^d	50.69 ± 1.80 ^g	76.38 ± 0.82 ^e
LSD (p < 0.05)		1.95	1.40	2.62	3.40	1.51	9.42

* a-s The statistical analysis as the mean comparison; Means with the same letter in a column are not significantly different at p ≤ 0.05.