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. 2019 Apr 18;8(4):535. doi: 10.3390/jcm8040535

Table 2.

Main clinical features of a multicenter sample of 444 polypathological patients recruited for sarcopenia and frailty assessment.

Clinical Features Mean (SD)/Median [IQR]/N (%)
Number of defining categories per patient 2.5 (0.8)
 Patients with ≥ 3 categories 175 (39.5%)
Prevalence of defining categories in recruited polypathological patients
 Category A (heart diseases) 374 (84.6%)
 Category B (kidney/autoimmune diseases) 202 (45.7%)
 Category C (lung diseases) 183 (41.4%)
 Category E (neurological diseases) 133 (30.1%)
 Category F (peripheral arterial disease/diabetes with neuropathy) 80 (18.1%)
 Category G (chronic neoplasia/anemia) 70 (15.8%),
 Category H (degenerative osteoarticular disease) 43 (9.7%)
 Category D (liver disease) 28 (6.3%)
Number of other comorbidities per patient 5.9 (2.3)
 Cardiovascular 1.8 (0.9)
 Endocrine and metabolic 1.6 (1)
 Respiratory 0.75 (0.9)
Most frequent comorbidities
 Hypertension 380 (86%)
 Dyslipemia 232 (52.5%)
 Diabetes with no visceral involvement 216 (49%)
 Atrial fibrillation 178 (40%)
 Obesity 159 (36%)
 Anxiety and depressive disorders 74 (17%)
 Benign prostate hyperplasia 64 (14.5%)
 Osteoporosis 42 (9.5%)
Frequent symptoms
 Fatigue 304 (70%)
 Anorexia 212 (48%)
 Insomnia 194 (44%)
 Chronic pain 178 (40%)
 Cough 158 (36%)
 Patients with basal III-IV class of NYHA // III-IV class of mMRC 128 (29%)
 Patients with delirium in last hospital admission 76 (17%)
 Nausea/Vomiting 37 (8.5%)
 Pressure ulcer(s) 35 (8%)
PROFUND index 6 [6]
Number of prescribed drugs at inclusion / Patients with polypharmacy 10 (4)/429 (96.5%)
Patients with home oxygen therapy 74 (17%)
Hospitalizations in last 3 months / total days in hospital in last 3 months 0.6 (0.8)/5 (9)
Basal Barthel´s Index 66 (30)

SD: standard deviation; IQR: interquartile range; NYHA: New York Heart Association; mMRC: Medical Research Council.