Table 3.
Quality of Life and Disease scores for Patient 1, pre-therapy and during EE-TP therapy.
| Scale | Months of Therapy | ||
|---|---|---|---|
| Pre-Therapy | 7 | 24 | |
| SF36 (health and well-being): | |||
| Physical component (population mean 50 ± 10) | 47 | 52 | 42 |
| Mental component (population mean 50 ± 10) | 43 | 45 | 42 |
| Newcastle mitochondrial disease scale (normal = 0): | |||
| I (general neurological functioning, 0 to 50) | 4 | 4 | 16 |
| II (system specific functioning, 0 to 45) | 6 | 6 | 6 |
| III (clinical assessment, 0 to 50) | 8 | 8 | 19 |
| MRC sum motor score | |||
| (normal = 80) | 73 | 73 | 53 |
| Overall neuropathy limitation scale: | |||
| (0 = no disability, 12 = maximum disability) | 4 | 4 | 4 |
| Sensory sum score: | |||
| (normal = 0, maximum score = 64) | 26 | 26 | 34 |