Table 3.
Distribution frequency of the clinical status and H19 rs2177727 genotype frequencies in 431 UCC patients.
| H19 (rs2177727) | ||||
|---|---|---|---|---|
| Variable | CC (%) (n = 185) | CT+TT (%) (n = 246) | OR (95% CI) | p Value |
| Stage | ||||
| Non muscle invasive tumor (pTa–pT1) | 112 (60.5%) | 123 (50%) | 1.000 (reference) | |
| Muscle invasive tumor (pT2–pT4) | 73 (39.5%) | 123 (50%) | 1.534 (1.042–2.258) | 0.030 |
| Tumor T status | ||||
| Ta | 41 (22.2%) | 49 (19.9%) | 1.000 (reference) | |
| T1–T4 | 144 (77.8%) | 197 (80.1%) | 1.145 (0.717–1.826) | 0.571 |
| Lymph node status | ||||
| N0 | 165 (89.2%) | 215 (87.4%) | 1.000 (reference) | |
| N1+N2 | 20 (10.8%) | 31 (12.6%) | 1.190 (0.654–2.162) | 0.569 |
| Metastasis | ||||
| M0 | 179 (96.8%) | 238 (96.7%) | 1.000 (reference) | |
| M1 | 6 (3.2%) | 8 (3.3%) | 1.003 (0.342–2.941) | 0.996 |
| Histopathologic grading | ||||
| Low grade | 22 (11.9%) | 31 (12.6%) | 1.000 (reference) | |
| High grade | 163 (88.1%) | 215 (87.4%) | 0.936 (0.523–1.677) | 0.824 |
Bold font indicates statistical significance (p < 0.05). The OR with their 95% CI were estimated by logistic regression models.