Table 5.
Risk of disease-specific mortality on genotype distributions of H19 gene polymorphisms among 264 UCC patients over 65 years old.
| Variable | N | Number of Disease-Specific Mortality | HR (95% CI) | AHR (95% CI) |
|---|---|---|---|---|
| rs2177727 | ||||
| CC | 112 | 17 | 1.000 (reference) | 1.000 (reference) |
| CT+TT | 152 | 30 | 1.308 (0.721–2.373) | 1.404 (0.770–2.561) |
| rs2107425 | ||||
| CC | 93 | 11 | 1.000 (reference) | 1.000 (reference) |
| CT+TT | 171 | 36 | 1.862 (0.948–3.659) | 2.043 (1.029–4.059) |
| rs2839698 | ||||
| CC | 128 | 27 | 1.000 (reference) | 1.000 (reference) |
| CT+TT | 136 | 20 | 0.669 (0.375–1.195) | 0.668 (0.374–1.194) |
| rs3024270 | ||||
| CC | 75 | 14 | 1.000 (reference) | 1.000 (reference) |
| GC+GG | 189 | 33 | 0.934 (0.499–1.749) | 0.892 (0.470–1.691) |
| rs3741219 | ||||
| AA | 120 | 25 | 1.000 (reference) | 1.000 (reference) |
| GA+GG | 144 | 22 | 0.678 (0.382–1.204) | 0.683 (0.383–1.217) |
Bold font indicates statistical significance (p < 0.05). The hazrds ratio (HR) with their 95% CI were estimated by Cox proportional hazards model. The adjusted hard ratio (AHR) with their 95% CI were estimated by multiple Cox proportional hazards model after controlling for age, sex, and tobacco consumption.