Table 4.
Model of inheritance | Group | I2 (%) | Fixed effect model | Random effect model | ||||||
---|---|---|---|---|---|---|---|---|---|---|
z | p | OR(95%CI) | z | p | OR(95%CI) | |||||
Dominant | GG /GA versus AA | Overall | 67.4 | 1.67 | 0.096 | 1.17 (0.97, 1.42) | 1.12 | 0.263 | 1.26 (0.84, 1.89) | |
Asian | 72.1 | 3.12 | 0.002 | 1.46 (1.15, 1.85) | 1.98 | 0.048 | 1.86 (1.01, 3.45) | |||
SCA | 1.8 | 1.48 | 0.140 | 0.79 (0.57, 1.08) | 1.43 | 0.153 | 0.79 (0.57, 1.09) | |||
Recessive | GG versus GA/AA | Overall | 28.1 | 2.57 | 0.010 | 0.44 (0.23, 0.82) | 1.59 | 0.112 | 0.47 (0.19, 1.19) | |
Asian | 47.2 | 0.40 | 0.691 | 0.83 (0.33, 2.07) | 0.21 | 0.834 | 1.22 (0.20, 7.51) | |||
SCA | 3.1 | 2.67 | 0.008 | 0.27 (0.10, 0.70) | 2.29 | 0.022 | 0.30 (0.11, 0.84) | |||
Codominant | GG versus AA | Overall | 33.0 | 2.63 | 0.009 | 0.43 (0.23, 0.81) | 1.54 | 0.122 | 0.46 (0.18, 1.23) | |
Asian | 54.3 | 0.27 | 0.786 | 0.88 (0.36, 2.18) | 0.34 | 0.732 | 1.41 (0.20, 10.26) | |||
SCA | 0.0 | 2.84 | 0.005 | 0.24 (0.09, 0.64) | 2.57 | 0.010 | 0.27 (0.10, 0.73) | |||
GA versus AA | Overall | 63.3 | 2.46 | 0.014 | 1.28 (1.05, 1.56) | 1.62 | 0.104 | 1.38 (0.94, 2.04) | ||
Asian | 68.1 | 3.24 | 0.001 | 1.49 (1.17, 1.90) | 2.02 | 0.043 | 1.82 (1.02, 3.26) | |||
SCA | 28.5 | 0.37 | 0.709 | 0.94 (0.67, 1.32) | 0.32 | 0.746 | 0.94 (0.62, 1.40) | |||
Superdominant | GA versus GG/AA | Overall | 59.9 | 2.80 | 0.005 | 1.32 (1.09, 1.61) | 1.84 | 0.065 | 1.42 (0.98, 2.06) | |
Asian | 67.1 | 3.26 | 0.001 | 1.50 (1.17, 1.91) | 2.04 | 0.042 | 1.81 (1.02, 3.21) | |||
SCA | 17.6 | 0.21 | 0.833 | 1.04 (0.74, 1.45) | 0.19 | 0.850 | 1.04 (0.71, 1.51) |