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. 2019 Apr 25;16(8):1475. doi: 10.3390/ijerph16081475

Table 4.

Sensitivity analysis under different inheritance models through adopting different effect models.

Model of inheritance Group I2 (%) Fixed effect model Random effect model
z p OR(95%CI) z p OR(95%CI)
Dominant GG /GA versus AA Overall 67.4 1.67 0.096 1.17 (0.97, 1.42) 1.12 0.263 1.26 (0.84, 1.89)
Asian 72.1 3.12 0.002 1.46 (1.15, 1.85) 1.98 0.048 1.86 (1.01, 3.45)
SCA 1.8 1.48 0.140 0.79 (0.57, 1.08) 1.43 0.153 0.79 (0.57, 1.09)
Recessive GG versus GA/AA Overall 28.1 2.57 0.010 0.44 (0.23, 0.82) 1.59 0.112 0.47 (0.19, 1.19)
Asian 47.2 0.40 0.691 0.83 (0.33, 2.07) 0.21 0.834 1.22 (0.20, 7.51)
SCA 3.1 2.67 0.008 0.27 (0.10, 0.70) 2.29 0.022 0.30 (0.11, 0.84)
Codominant GG versus AA Overall 33.0 2.63 0.009 0.43 (0.23, 0.81) 1.54 0.122 0.46 (0.18, 1.23)
Asian 54.3 0.27 0.786 0.88 (0.36, 2.18) 0.34 0.732 1.41 (0.20, 10.26)
SCA 0.0 2.84 0.005 0.24 (0.09, 0.64) 2.57 0.010 0.27 (0.10, 0.73)
GA versus AA Overall 63.3 2.46 0.014 1.28 (1.05, 1.56) 1.62 0.104 1.38 (0.94, 2.04)
Asian 68.1 3.24 0.001 1.49 (1.17, 1.90) 2.02 0.043 1.82 (1.02, 3.26)
SCA 28.5 0.37 0.709 0.94 (0.67, 1.32) 0.32 0.746 0.94 (0.62, 1.40)
Superdominant GA versus GG/AA Overall 59.9 2.80 0.005 1.32 (1.09, 1.61) 1.84 0.065 1.42 (0.98, 2.06)
Asian 67.1 3.26 0.001 1.50 (1.17, 1.91) 2.04 0.042 1.81 (1.02, 3.21)
SCA 17.6 0.21 0.833 1.04 (0.74, 1.45) 0.19 0.850 1.04 (0.71, 1.51)