Table 2.
A subset1 of gene ontology (GO) enrichment and annotated genes within sweeps of inter-population FST; (a) North- vs. East-African populations2 and (b) Baladi–Fayoumi vs. Dandarawi.
| GO:Term | GO:ID | Genes |
|---|---|---|
| (a) North- vs. East-African populations | ||
| Cell differentiation | GO:0030154 | SFRP2, PCK1, Pcdh15, NTRK3, MAPK9, NRP1, NGF, MYH9, MYL6, MYOG, MYBPC3 |
| (b) Baladi–Fayoumi vs. Dandarawi | ||
| Autophagy | GO:0006914 | GABARAPL2, ATG5, VPS11 |
| Cellular response to oxygen radical | GO:0071450 | NQO1, SOD1, SOD2, SOD3, MNSOD, PRDX1 |
| Endosome to melanosome transport | GO:0035646 | AP1G1, RAB38, RAB32, ANKRD27, AP1M1 |
| Melanosome organization | GO:0032438 | AP1G1, HPS4, RAB38 |
| Negative regulation of telomere maintenance | GO:0032205 | TERF1, TERF2, TERF2IP, RTEL1, CTC1 |
| Nitric oxide biosynthetic process | GO:0006809 | NQO1, SLC7A2, NOS1, NOS2 |
| Positive regulation of natural killer cell mediated cytotoxicity | GO:0045954 | AP1G1, LAMP1, IL12B, IL12A, IL18RAP |
| Regulation of skeletal muscle fiber development | GO:0048742 | ZFHX3, MYOG, MYF5, MYF6, MYOD1 |
| Regulation of telomere maintenance | GO:0032204 | TERF2IP, MRE11, TERF1, TERF2, TERF2IP, RTEL1, CTC1 |
| Superoxide metabolic process | GO:0006801 | NQO1, SOD1, SOD2, SOD3, NOS2, MNSOD |
1The subset of GO that affect adaptation profile to cellular or environmental stressors. 2North-African populations group is composed of Baladi, Fayoumi, and Dandarawi populations’ samples; while East-African population group is composed of Rwanda and Uganda populations’ samples.