Figure 2.

Characterization of fabricated microparticles. Representative SEM images of (A) phagocytsoable MPs and (B) nonphagocytosable MPs show size and surface morphology. (C) Size distributions of phagocytosable MPs (vitamin D₃ or insulin) and nonphagocytosable MPs (TGF-β1 or GM-CSF) were confirmed by dynamic light scattering, reporting mean and standard deviation in the legend (n = 5). (D) Release kinetics of encapsulated factors from biodegradable PLGA MPs over 28 days, as determined by ELISA or spectrophotometry (n = 3–5). (E) The loading efficiencies of encapsulated agents and mass delivered per 2.5 mg of PLGA injection is calculated. Data are represented by the mean ± SEM.