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. 2019 Apr 14;8(4):512. doi: 10.3390/jcm8040512

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

(a) Representative Cu-64 PET data of National Electrical Manufacturers Association (NEMA) NU4-2008 phantom. The reconstruction algorithms used were filtered back projection (FBP) (ramp filter), FBP (Butterworth filter), FBP-3DRP, 2D ordered subset expectation maximization (OSEM 2D) (iteration 1), and OSEM3D-MAP (β = 0.1). These data were presented for partially corrected data. (b) Non-uniformity for various reconstruction algorithms, such as FBP, FBP-3DRP, OSEM2D, and OSEM3D-MAP reconstruction with filters. Normalization, dead-time, and random corrections have been applied to all PET raw data. The effects of attenuation correction (AC), and AC and scatter correction (SC) corrections in PET were also provided. The term “partially corrected” meant that normalization, dead-time, and random correction were performed. AC: attenuation correction, SC: scatter correction, 3DRP: FBP-3DRP, MAP: OSEM3D-MAP.