Table 3.

Model-based change scores by treatment arm and phase, stratified by age

	Under 65
	Delayed On		Early On
Outcome	Phase 1	Phase 2	Phase 1	Phase 2
ADAS-cog 13	10.51(3.66)	7.57(5.51)	17.13(3.50)	−.26(3.27)
CDRsb	.45(.43)	3.61(1.40)	3.07(.73)	4.07(1.40)
CVLT	−8.36(3.24)	−3.96(2.34)	−5.28(1.42)	−6.03(2.59)
NPI	7.46(5.52)	2.59(3.71)	12.26(3.02)	2.16(4.06)
	Over 65
ADAS-cog 13	7.41(2.05)	5.70(1.81)	3.99(1.14)	8.14(1.90)
CDRsb	3.45(.78)	2.20(.62)	2.13(.45)	1.38(.46)
CVLT	−2.73(1.20)	−3.76(1.66)	−3.83(1.28)	−1.83(1.81)
NPI	5.95(2.17)	.97(1.77)	2.86(1.37)	−1.32(1.36)

Note: values are fitted change per year (SE)