Table 2.
Results of the Family Based Association Test Analysis in children with influenza using PBAT for individual SNPs and HBAT for haplotypes.
| SNP (allele) | Frequency | Families | Z-Score | P-value∧ | Power* |
|---|---|---|---|---|---|
| H (rs11003125) | 0.39 | 166 | −1.74 | 0.08 | 0.05 |
| L | 0.61 | +1.74 | |||
| Y (rs7096206) | 0.84 | 126 | −0.34 | 0.73 | 1.00 |
| X | 0.16 | +0.34 | |||
| B (rs1800450) | 0.14 | 104 | +1.66 | 0.10 | 1.00 |
| Wild Type | 0.86 | −1.66 | |||
| C (rs1800451) | 0.05 | 36 | −1.76 | 0.08 | 1.00 |
| Wild Type | 0.95 | +1.76 | |||
| D (rs5030737) | 0.05 | 51 | −0.14 | 0.89 | 1.00 |
| Wild Type | 0.95 | +0.14 | |||
| Haplotype | Frequency | Families | Z-Score | P-value∧ | |
| HYA | 0.34 | 158 | −1.73 | 0.08 | – |
| LYA | 0.25 | 151 | 0.75 | 0.45 | – |
| LXA | 0.16 | 121 | 0.53 | 0.60 | – |
| LYB | 0.14 | 97 | 1.88 | 0.06 | – |
| LYC | 0.05 | 31 | −1.72 | 0.09 | – |
| HYD | 0.05 | 45 | 0.17 | 0.87 | – |
*
Calculated using the Additive Model in PBAT.
∧
p-values are using the Additive Model.