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. 2019 May 14;14:92. doi: 10.1186/s13019-019-0911-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Calcium-induced swelling of SSM. Ca²⁺-induced swelling of SSM without (a) and with (b) pyruvate-dependent blocking of mPTP. Arrows indicate the earliest pair (IR/30 vs. IR15/30, IR 30/30, IR 40/30) of significantly different observations during reperfusion. Values are presented as means ± standard error of the mean; *p ≤ 0.05. SSM: subsarcolemmal mitochondria; mPTP: mitochondrial permeability transition pore